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In-Vitro Fertilization - Embryo Transfer
(IVF-ET)
STEP 5 - LUTEAL PHASE AND PREGNANCY MONITORING
Hormone levels are monitored after embryo replacement. Progesterone is a hormone normally secreted from the ovaries following ovulation. Progesterone has several important functions, but perhaps one of its most important is the development of a lining in the uterus capable of sustaining pregnancy. Progesterone supplementation needs to be taken by injection or by vaginal suppositories. Progesterone is started on the day of the egg retrieval and is taken until pregnancy is confirmed. Occasionally, it is also necessary to monitor serum estradiol levels after embryo transfer.
A pregnancy test (b-hCG level) will be done after
10-12 days following embryo transfer.
Once the pregnancy test is positive, the progesterone should be continued for approximately 6 to 8 weeks until the placenta is capable of producing enough progesterone on its own to support the pregnancy. Side effects of progesterone supplementation include breast tenderness, weight gain, localized pain and lump formation at the injection site. Once a pregnancy is confirmed with a blood test, an ultrasound examination will be performed to ensure that the pregnancy is located within the uterus and is growing normally.
In the event of an unsuccessful cycle, the couple will be seen in a follow-up appointment for a comprehensive
re-evaluation and review of the cycle to plan future treatments. Much information can be learned during a treatment cycle which can be used to enhance the likelihood for achieving pregnancy in a subsequent cycle.
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